Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis

Fungi from the genus Candida are common members of the human microbiota; however, they are also important opportunistic pathogens in immunocompromised hosts. Several morphological transitions have been linked to the ability of these fungi to occupy the different ecological niches in the human body. The transcription factor Efg1 from the APSES family plays a central role in the transcription cir...

متن کامل

Investigation the expression Candida albicans EFG1 gene in Vaginal Candidiasis and biofilm formation

Candida albicans has the ability to change between yeast and hyphal cells and is known to be a virulence property. Efg1gene of C.albicans is as a main transcription factor that plays pivotal roles in biofilm formation The aim of the current study is to investigate the presence of Efg1 gene in Candida albicans isolates from women with vaginal candidiasis and its impact on biofilm formation.We us...

متن کامل

The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis

Efg1 (a member of the APSES family) is an important regulator of hyphal growth and of the white-to-opaque transition in Candida albicans and very closely related species. We show that in Candida parapsilosis Efg1 is a major regulator of a different morphological switch at the colony level, from a concentric to smooth morphology. The rate of switching is at least 20-fold increased in an efg1 kno...

متن کامل

Mds3 regulates morphogenesis in Candida albicans through the TOR pathway.

The success of Candida albicans as a major human fungal pathogen is dependent on its ability to colonize and survive as a commensal on diverse mucosal surfaces. One trait required for survival and virulence in the host is the morphogenetic yeast-to-hypha transition. Mds3 was identified as a regulator of pH-dependent morphogenesis that functions in parallel with the classic Rim101 pH-sensing pat...

متن کامل

Protoplasts Obtained from Candida tropicalis

A method for the preparation of protoplasts from Candida tropicalis cultivated on n-tetradecane is described. This essentially consists of replacing the mannitolsorbitol solution of the classical helicase technique by 1 M magnesium sulfate and lowering the pH to 4.1 during incubation in the presence of helicase. The protoplasts thus prepared behave like intact cells and are capable of consuming...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: G3 Genes|Genomes|Genetics

سال: 2015

ISSN: 2160-1836

DOI: 10.1534/g3.115.017566